Ortho Sleep was formulated to be the most comprehensively powerful natural sleep-aid available. Ortho Sleep’s ingredients have been clinically proven to reduce the latency and increase the quality of sleep.Insomnia – as a symptom of modern stress – plagues about one in seven people at any given time, and most people will endure at least a temporary bout of some type of sleep disorder at least once in their lifetime. In addition to impaired cognitive and physical performance, insomnia can also lead to depression, increased accident risk and even heart disease.Sleep is regulated by the body’s internal clock, which keeps track of light levels, the time of day and other important cues for sleep and awakening. There are two primary types of sleep; REM (Rapid Eye Movement) sleep, which is dreaming sleep, and Non-REM sleep, which consists of four stages of progressively deeper sleep, all of which precede REM sleep. While all sleep stages are important, stages III and IV of deep sleep and REM sleep are especially vital.Many people have trouble sleeping or have disrupted sleep patterns. People suffering from insomnia spend less time in deeper levels of sleep, wake up more often, and experience a reduction in REM sleep. In addition to stress, insomnia can be caused by a variety of other factors, including anxiety, poor diet, or a disruption of the body’s internal clock – such as jet lag, all-night study sessions, or changing work hours. NeurotransmittersNeurotransmitters are the key to sleep regulation. These chemicals are like tiny messengers in the brain, transmitting signals from one neuron to another and modulating a huge number of functions in the human body, including sleep. Gamma-aminobutyric acid (or GABA) is the most important inhibitory neurotransmitter in the brain. GABA acts like a “brake” during times of stress or anxiety, regulating brain excitability and inducing relaxation. GABA receptors are highly concentrated in the hypothalamus; the region of the brain associated with sleep. GABA is effective against insomnia, and has been shown to affect the brain directly, increasing a-brain waves (those associated with relaxation) and reducing ß-brain waves (those associated with anxiety and stress).Serotonin and melatonin are also key neurotransmitters. Melatonin is produced by the pineal gland in the brain, and it controls the body’s internal clock. Melatonin has been shown to increase sleep time and reduce the time it takes to fall asleep. It can also help to reset the body’s sleep-wake cycle, a benefit to those suffering from jet lag or a similar disruption. Supplemental melatonin’s effects on sleep are extensive and well documented.Supplemental melatonin is particularly well-researched with respect to dealing with disruptions in the body’s internal clock, such as jet lag and shift work, with no fewer than 10 clinical studies demonstrating it’s ability to resynchronize the body’s altered circadian rhythms governing sleep.Serotonin is essential for sleep modulation in its own right, and can also be converted by the body into melatonin. 5-HTP is (L)5-hyrdoxytryptophan, a metabolite of the amino acid tryptophan and a precursor to serotonin and melatonin. 5-HTP boosts serotonin levels, and can also increase REM and deep sleep phases, making sleep more restful. Supplemental 5-HTP has been successfully studied for the treatment of a number of conditions, including mood balance, chronic fatigue, and migraines. Studies examining its positive effects on sleep go back to the early 1970’s, and a recent study revealed that 5-HTP supplementation was able to reduce the number of sleep-terror episodes in children by nearly 84%.
2 capsules contain:
GABA (Gamma Aminobutyric Acid) 100mg
L-5-Hydroxytryptophan (Griffonia Seed) 100mg
Valerian Root (0.8% Valerenic acid) 150mg
Passionflower (3.5% Vitexin) 32mg
CYRACOSTM (lemon balm extract)† 300mg
Do not use if pregnant or nursing.
Take 1-2 capsules before bedtime or as directed by a qualified health care practitioner.
60 vegetarian capsules
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